Search results for "Single chain"

Antiidiotypic DNA vaccination induces serum bactericidal activity and protection against group B meningococci

2006

No vaccine is available for preventing infections by serogroup B Neisseria meningitidis (MenB), which accounts for a major portion of meningococcal cases in developed countries, because of the poor immunogenicity of the capsular polysaccharide (CP) even after protein conjugation. We have previously induced anticapsular antibodies by immunization with a single chain variable fragment (scFv), which mimics a protective CP epitope. This surrogate antigen, however, was ineffective at inducing serum bactericidal activity, an accepted marker of protection in humans. Serum bactericidal activity was consistently achieved by immunizing mice with the scFv-encoding gene. Immunization with vectors witho…

Dynamic Self-Consistent Field Approach for Studying Kinetic Processes in Multiblock Copolymer Melts

2020

The self-consistent field theory is a popular and highly successful theoretical framework for studying equilibrium (co)polymer systems at the mesoscopic level. Dynamic density functionals allow one to use this framework for studying dynamical processes in the diffusive, non-inertial regime. The central quantity in these approaches is the mobility function, which describes the effect of chain connectivity on the nonlocal response of monomers to thermodynamic driving fields. In a recent study [Mantha et al, Macromolecules 53, 3409 (2020)], we have developed a method to systematically construct mobility functions from reference fine-grained simulations. Here we focus on melts of linear chains …

Cobalt(II)-Copper(II) Bimetallic Chains as a New Class of Single-Chain Magnets

2004

Organic Dye Bearing Asymmetric Double Donor-π-Acceptor Chains for Dye-Sensitized Solar Cells

2011

A novel efficient metal free sensitizer containing asymmetric double donor-π-acceptor chains (DC) was synthesized for dye-sensitized solar cells (DSSCs). Comparing to 3.80%, 4.40% and 4.64% for the DSSCs based on the dyes with single chain (SC1, SC2) and cosensitizers (SC1 + SC2), the overall conversion efficiency reaches 6.06% for DC-sensitized solar cells as a result of its longer electron lifetime and higher incident monochromatic photon-to-current conversion efficiency.

Monte Carlo Simulations of Semi-Flexible Polymers

2005

We present Monte Carlo simulations on the phase behavior of semiflexible macromolecules. For a single chain this question is of biophysical interest given the fact that long and stiff DNA chains are typically folded up into very tight compartments. So one can ask the question how the state diagram of a semiflexible chain differs from the coilglobule behavior of a flexible macromolecule. Another effect connected with rigidity of the chains is their tendency to aggregate and form nematically ordered structures. As a consequence one has two competing phase transitions: a gas-liquid and an isotropic-nematic transition potentially giving rise to a complicated phase diagram.

Single chain magnet behaviour in an enantiopure chiral cobalt(II)–copper(II) one-dimensional compound

2010

The self-assembly of an enantiomerically pure, chiral dianionic oxamatocopper(II) complex with cobalt(II) ions leads to neutral oxamato-bridged heterobimetallic chains that combine chirality and slow magnetic relaxation, providing thus the first example of ‘‘chiral single chain magnets (CSCMs). Ruiz Garcia, Rafael, Rafael.Ruiz@uv.es ; Lloret Pastor, Francisco, Francisco.Lloret@uv.es

Molecular Engineering To Control the Magnetic Interaction between Single-Chain Magnets Assembled in a Two-Dimensional Network

2012

International audience; Two two-dimensional (2D) systems having the formula [{Fe-III(dmbpy)(CN)(4)}(2)(CoL)-L-II](n) [L = pyetNO (1), tvpNO (2)] and consisting of single-chain magnets connected through organic ligands (L) have been prepared, and their magnetic properties have been investigated. The overall magnetic behavior depends on the capacity of the organic pillars to transmit long-range magnetic interactions. 1 is the first example of a 2D compound exhibiting double relaxation of the magnetization, whereas 2 behaves as a metamagnet.

Study of the conformations of the molecules in amorphous polymers by computer simulation

2008

It is investigated by computer simulation whether space problems prevent a closing packing of chain molecules if the chain molecules are randomly coiled. Chains consisting of 100 beads were introduced into a primitive cubic lattice in such a way that each lattice point is occupied by not more than one bead. It was possible to occupy up to 88% of the lattice points. The average square end-to-end distance of the chains in the concentrated system is the same as for a single chain. Neither perfect chain bundles nor imperfect chain bundles occur in a considerable amount. This shows that it is possible to pack closely randomly coiled chains.

Phase transitions in a single polymer chain: A micro-canonical analysis of Wang–Landau simulations

2008

Abstract We present simulation results for the phase behavior of a single chain for a flexible lattice polymer model using the Wang–Landau sampling idea. Using the micro-canonical density of states obtained with this method we will discuss the ability of an analysis in the micro-canonical ensemble to locate the coil-globule (continuous) and liquid–solid (first-order) transitions found for this problem using a canonical analysis.

Halo and Pseudohalo Cu(I)-Pyridinato Double Chains with Tunable Physical Properties

2015

The properties recently reported on the Cu(I)-iodide pyrimidine nonporous 1D-coordination polymer [CuI(ANP)] (ANP = 2-amino-5-nitropyridine) showing reversible physically and chemically driven electrical response have prompted us to carry a comparative study with the series of [CuX(ANP)] (X = Cl (1), X = Br (2), X = CN (4), and X = SCN (5)) in order to understand the potential influence of the halide and pseudohalide bridging ligands on the physical properties and their electrical response to vapors of these materials. The structural characterization of the series shows a common feature, the presence of -X-Cu(ANP)-X- (X = Cl, Br, I, SCN) double chain structure. Complex [Cu(ANP)(CN)] (4) pre…